Kshirsagar, Rashmi : rechercher sur Z-Library

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1

Concentrated fed-batch cell culture increases manufacturing capacity without additional volumetric capacity

Yang, William C., Minkler, Daniel F., Kshirsagar, Rashmi, Ryll, Thomas, Huang, Yao-Ming

Journal:

Journal of Biotechnology

Année:

2016

Langue:

english

Fichier:

PDF, 459 KB

english, 2016

2

Addition of Valproic Acid to CHO Cell Fed-Batch Cultures Improves Monoclonal Antibody Titers

Yang, William C., Lu, Jiuyi, Nguyen, Ngan B., Zhang, An, Healy, Nicholas V., Kshirsagar, Rashmi, Ryll, Thomas, Huang, Yao-Ming

Journal:

Molecular Biotechnology

Année:

2014

Langue:

english

Fichier:

PDF, 349 KB

english, 2014

3

[Advances in Biochemical Engineering/Biotechnology] || Innovation in Cell Banking, Expansion, and Production Culture

Kshirsagar, Rashmi

Année:

2016

Langue:

english

Fichier:

PDF, 436 KB

english, 2016

4

Multi-Omics Study on the Impact of Cysteine Feed Level on Cell Viability and mAb Production in a CHO Bioprocess

Ali, Amr S., Raju, Ravali, Kshirsagar, Rashmi, Ivanov, Alexander R., Gilbert, Alan, Zang, Li, Karger, Barry L.

Journal:

Biotechnology Journal

Année:

2018

Langue:

english

Fichier:

PDF, 1022 KB

english, 2018

5

Advanced process monitoring and feedback control to enhance cell culture process production and robustness

Zhang, An, Tsang, Valerie Liu, Moore, Brandon, Shen, Vivian, Huang, Yao-Ming, Kshirsagar, Rashmi, Ryll, Thomas

Journal:

Biotechnology and Bioengineering

Année:

2015

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2015

6

Application of high-throughput mini-bioreactor system for systematic scale-down modeling, process characterization, and control strategy development

Janakiraman, Vijay, Kwiatkowski, Chris, Kshirsagar, Rashmi, Ryll, Thomas, Huang, Yao-Ming

Journal:

Biotechnology Progress

Année:

2015

Langue:

english

Fichier:

PDF, 537 KB

english, 2015

7

Characterization of trisulfide modification in antibodies

Sheng Gu, Dingyi Wen, Paul H. Weinreb, Yaping Sun, Lihe Zhang, Susan F. Foley, Rashmi Kshirsagar, David Evans, Sha Mi, Werner Meier, R. Blake Pepinsky

Journal:

Analytical Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 796 KB

english, 2010

8

Investigation of metabolic variability observed in extended fed batch cell culture

Gilbert, Alan, McElearney, Kyle, Kshirsagar, Rashmi, Sinacore, Martin S., Ryll, Thomas

Journal:

Biotechnology Progress

Année:

2013

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2013

9

Perfusion seed cultures improve biopharmaceutical fed-batch production capacity and product quality

Yang, William C., Lu, Jiuyi, Kwiatkowski, Chris, Yuan, Hang, Kshirsagar, Rashmi, Ryll, Thomas, Huang, Yao-Ming

Journal:

Biotechnology Progress

Année:

2014

Langue:

english

Fichier:

PDF, 633 KB

english, 2014

10

Human cell lines for biopharmaceutical manufacturing: history, status, and future perspectives

Dumont, Jennifer, Euwart, Don, Mei, Baisong, Estes, Scott, Kshirsagar, Rashmi

Journal:

Critical Reviews in Biotechnology

Année:

2015

Langue:

english

Fichier:

PDF, 545 KB

english, 2015

11

Leveraging high-throughput technology to accelerate the time to clinic: A case study of a mAb

Siva, Sethu, Zhang, An, Koepf, Edward, Conley, Lynn, Cecchini, Doug, Huang, Yao-Ming, Kshirsagar, Rashmi, Ryll, Thomas

Journal:

Engineering in Life Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 620 KB

english, 2016

12

Glucose Monitoring and Adaptive Feeding of Mammalian Cell Culture in the Presence of Strong Autofluorescence by near Infrared Raman Spectroscopy

Matthews, Thomas E., Smelko, John P., Berry, Brandon, Romero-Torres, Saly, Hill, Dan, Kshirsagar, Rashmi, Wiltberger, Kelly

Journal:

Biotechnology Progress

Année:

2018

Langue:

english

Fichier:

PDF, 776 KB

english, 2018

13

Controlling trisulfide modification in recombinant monoclonal antibody produced in fed-batch cell culture

Rashmi Kshirsagar, Kyle McElearney, Alan Gilbert, Marty Sinacore, Thomas Ryll

Journal:

Biotechnology and Bioengineering

Année:

2012

Langue:

english

Fichier:

PDF, 448 KB

english, 2012

14

Analysis of dynamic changes in the proteome of a Bcl-XL overexpressing Chinese hamster ovary cell culture during exponential and stationary phases

Tyler Carlage, Rashmi Kshirsagar, Li Zang, Vijay Janakiraman, Marina Hincapie, Yelena Lyubarskaya, Andy Weiskopf, William S. Hancock

Journal:

Biotechnology Progress

Année:

2012

Langue:

english

Fichier:

PDF, 592 KB

english, 2012

15

Effects of pH probe lag on bioreactor mixing time estimation

Zhang, An, Tsang, Valerie Liu, Korke-Kshirsagar, Rashmi, Ryll, Thomas

Journal:

Process Biochemistry

Année:

2014

Langue:

english

Fichier:

PDF, 876 KB

english, 2014

16

Manufacturing process used to produce long-acting recombinant factor VIII Fc fusion protein

McCue, Justin, Kshirsagar, Rashmi, Selvitelli, Keith, Lu, Qi, Zhang, Mingxuan, Mei, Baisong, Peters, Robert, Pierce, Glenn F., Dumont, Jennifer, Raso, Stephen, Reichert, Heidi

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 474 KB

english, 2015

17

Quick generation of Raman spectroscopy based in-process glucose control to influence biopharmaceutical protein product quality during mammalian cell culture

Berry, Brandon N., Dobrowsky, Terrence M., Timson, Rebecca C., Kshirsagar, Rashmi, Ryll, Thomas, Wiltberger, Kelly

Journal:

Biotechnology Progress

Année:

2016

Langue:

english

Fichier:

PDF, 702 KB

english, 2016

18

Tryptophan oxidation catabolite, N -formylkynurenine, in photo degraded cell culture medium results in reduced cell culture performance

McElearney, Kyle, Ali, Amr, Gilbert, Alan, Kshirsagar, Rashmi, Zang, Li

Journal:

Biotechnology Progress

Année:

2016

Langue:

english

Fichier:

PDF, 467 KB

english, 2016

19

Integration of cell line and process development to overcome the challenge of a difficult to express protein

Alves, Christina S., Gilbert, Alan, Dalvi, Swati, Germain, Bryan St., Xie, Wenqi, Estes, Scott, Kshirsagar, Rashmi, Ryll, Thomas

Journal:

Biotechnology Progress

Année:

2015

Langue:

english

Fichier:

PDF, 941 KB

english, 2015

20

Identifying the differences in mechanisms of mycophenolic acid controlling fucose content of glycoproteins expressed in different CHO cell lines

Zhang, An, Tsang, Valerie Liu, Markely, Lam R., Kurt, Lutfiye, Huang, Yao-Ming, Prajapati, Shashi, Kshirsagar, Rashmi

Journal:

Biotechnology and Bioengineering

Année:

2016

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2016

21

Leveraging a CHO cell line toolkit to accelerate biotherapeutics into the clinic

Wright, Chapman, Alves, Christina, Estes, Scott, Pieracci, John, Kshirsagar, Rashmi

Journal:

Biotechnology Progress

Année:

2017

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2017

22

Lipidomics of CHO Cell Bioprocessing: Relation to Cell Growth and Specific Productivity of a Monoclonal Antibody

Ali, Amr S., Raju, Ravali, Ray, Somak, Kshirsagar, Rashmi, Gilbert, Alan, Zang, Li, Karger, Barry L.

Journal:

Biotechnology Journal

Année:

2018

Langue:

english

Fichier:

PDF, 850 KB

english, 2018

23

CHO Genome Mining for Synthetic Promoter Design

Johari, Yusuf B., Brown, Adam J., Alves, Christina S., Zhou, Yizhou, Wright, Chapman M., Estes, Scott D., Kshirsagar, Rashmi, James, David C.

Journal:

Journal of Biotechnology

Année:

2019

Langue:

english

Fichier:

PDF, 631 KB

english, 2019

24

Real-time Monitoring and Control of CHO Cell Apoptosis by In Situ Multifrequency Scanning Dielectric Spectroscopy

Ma, Fuduo, Zhang, An, Chang, David, Velev, Orlin D, Wiltberger, Kelly, Kshirsagar, Rashmi

Journal:

Process Biochemistry

Année:

2019

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2019

25

MultiâOmics Reveals Impact of Cysteine Feed Concentration and Resulting Redox Imbalance on Cellular Energy Metabolism and Specific Productivity in CHO Cell Bioprocessing

Ali, Amr S., Chen, Rachel, Raju, Ravali, Kshirsagar, Rashmi, Gilbert, Alan, Zang, Li, Karger, Barry L., Ivanov, Alexander R.

Journal:

Biotechnology Journal

Année:

2020

Langue:

english

Fichier:

PDF, 1.74 MB

english, 2020

26

Using Metabolomics to Identify Cell Line-Independent Indicators of Growth Inhibition for Chinese Hamster Ovary Cell-Based Bioprocesses

Alden, Nicholas, Raju, Ravali, McElearney, Kyle, Lambropoulos, James, Kshirsagar, Rashmi, Gilbert, Alan, Lee, Kyongbum

Journal:

Année:

2020

Fichier:

PDF, 504 KB

2020